Approach to Bruising 2018-01-30T16:36:29+08:00

Differential diagnosis

  • Congenital
    • Haemophilia
    • von Willebrand’s disease
    • Hereditary haemorrhagic telangiectasia
  • Endocrine
    • Cushing’s syndrome
  • Infection
    • Meningococcal infection
  • Coagulopathy
    • Production
      • Chronic liver disease
      • Vitamin K deficiency (malabsorption)
    • Consumption
      • Acquired haemophilia
      • Disseminated intravascular coagulation
  • Platelet dysfunction
    • Production disorders
      • Drug-induced (azathioprine, methotrexate etc.)
      • Primary marrow failure (e.g. secondary to malignancy)
    • Consumptive
      • Hypersplenism
      • Idiopathic thrombocytopaenic purpura
  • Inflammatory
    • Cryoglobulinaemia
    • Henoch-Schonlein purpura
  • Connective tissue disease
    • Marfan’s syndrome
    • Ehlers-Danlos syndrome
  • Neoplastic
    • Acute leukaemia
  • Drugs
    • Warfarin
    • Heparin
    • Anti-platelets
  • Pregnancy
    • HELLP syndrome
  • Social
    • Alcohol abuse
    • Non-accidental injury

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