ROCKET AF (2011): Rivaroxaban vs Warfarin in Atrial Fibrillation
Clinical question: in patients with atrial fibrillation, is rivaroxaban non-inferior to warfarin for the prevention of stroke or systemic embolism? Study design: multi-centre, randomized, double-blind, double-dummy, event-driven trial Inclusion criteria: Age ≥ 18 Non-valvular atrial fibrillation documented on ECG History of stroke, TIA or systemic embolism, or ≥ 2 of the following (i.e. CHADS2 ≥ 2) [...]